JaVale McGee had the most Blocks in a game in 2010-11 with 12.
That is 3 more blocks than second-place Serge Ibaka.
| Rk | Player | Team | Date | Blocks |
|---|---|---|---|---|
| 1 | JM JaVale McGee![]() | WAS | 2011-03-15 | 12 |
| 2 | SI Serge Ibaka![]() | OKC | 2011-04-27 | 9 |
| 3 | DH Dwight Howard![]() | ORL | 2010-11-03 | 8 |
| 4 | BL Brook Lopez![]() | NJN | 2011-03-05 | 8 |
| 5 | SI Serge Ibaka![]() | OKC | 2010-12-08 | 8 |
| 6 | SI Serge Ibaka![]() | OKC | 2011-03-14 | 8 |
| 7 | LS Larry Sanders![]() | MIL | 2010-12-01 | 8 |
| 8 | TD Tim Duncan![]() | SAS | 2010-12-15 | 7 |
| 9 | DM Darko Milicic![]() | MIN | 2010-12-10 | 7 |
| 10 | AJ Al Jefferson![]() | UTA | 2010-12-22 | 7 |
| 11 | JS Josh Smith![]() | ATL | 2010-11-16 | 7 |
| 12 | AB Andrew Bogut![]() | MIL | 2010-11-13 | 7 |
| 13 | AB Andrew Bogut![]() | MIL | 2010-12-15 | 7 |
| 14 | AB Andrew Bogut![]() | MIL | 2011-01-29 | 7 |
| 15 | AJ Amir Johnson![]() | TOR | 2011-03-01 | 7 |