Kobe Bryant led the NBA in Points in 2005-06 with 81.
That is 19 more points than second-place Kobe Bryant.
| Rk | Player | Team | Date | Value |
|---|---|---|---|---|
| 1 | Kobe Bryant | LAL | 2006-01-22 | 81 |
| 2 | Kobe Bryant | LAL | 2005-12-20 | 62 |
| 3 | Allen Iverson | PHI | 2005-12-23 | 53 |
| 4 | LeBron James | CLE | 2005-12-10 | 52 |
| 5 | Vince Carter | NJN | 2005-12-23 | 51 |
| 6 | LeBron James | CLE | 2006-01-21 | 51 |
| 7 | Kobe Bryant | LAL | 2006-04-07 | 51 |
| 8 | Kobe Bryant | LAL | 2006-01-19 | 51 |
| 9 | Dirk Nowitzki | DAL | 2006-03-23 | 51 |
| 10 | Kobe Bryant | LAL | 2006-01-07 | 50 |
| 11 | Kobe Bryant | LAL | 2006-04-14 | 50 |
| 12 | Kobe Bryant | LAL | 2006-05-04 | 50 |
| 13 | Dirk Nowitzki | DAL | 2006-06-01 | 50 |
| 14 | Paul Pierce | BOS | 2006-02-15 | 50 |
| 15 | Charlie Villanueva | TOR | 2006-03-26 | 48 |